One Two Three takes 3 different people - played by Tusshar Kapoor, Paresh Rawal and Suniel Shetty all in a hotel, all coming from very different backgrounds and with different personalities. So what brings them all together ? All of them have come to the same city, staying in the same hotel, and with the same name, Laxminarayan. And you can guess the rest of the confusion that erupts when they are all in the same hotel, especially when you have Dons also involved, and when one of them sells undergarments, you can understand where the adult humor comes in. Some of the other cast include Esha Deol, Sameera Reddy, Upen Patel, Neetu Chandra and Tanisha. A whole host of characters, but none of them are of the mega-star kind who would charge an arm and a leg, and who would throw a tantrum if you did not revolve the movie around them.
Tusshar is the poor guy from Mumbai, living with his widowed mother, with the ambition being to become more of a successful gangster, kill some people, make a name and then marry the daughter of another don. So, he comes to Pondicherry to kill another Don, on whom he has got a contract.
Suniel Shetty is a secretary, come to the city to buy a vintage car from a dealer (and who would not want to buy a car from a dealer such as Sameera Reddy).
Paresh Rawal is a dealer in undergarments, who has come to Pondicherry to meet up with a new supplier (Esha Deol). Both of these ladies have their own struggles, with both of them being under debt and desperate to strike the deals for which Suniel and Paresh have come to the city. And then Upen Patel and Tanisha are there in the auto showroom, but actually are doing diamonds, hiding in the car which Sameera is trying to sell. And of course, the police is also hunting for these diamonds. A sleeper movie (since not too many people remember the movie), but it made money and even though it is easy to dismiss as another of those crank comic capers, it did reasonably well.